تعداد نشریات | 161 |
تعداد شمارهها | 6,532 |
تعداد مقالات | 70,501 |
تعداد مشاهده مقاله | 124,114,904 |
تعداد دریافت فایل اصل مقاله | 97,218,780 |
اثرات مصرف متیونین محافظت شده در اواخر آبستنی بر فراسنجههای خون میشهای دوقلو آبستن پیش و پس از زایش | ||
مجله تحقیقات دامپزشکی (Journal of Veterinary Research) | ||
مقاله 7، دوره 72، شماره 4، دی 1396، صفحه 435-446 اصل مقاله (265.09 K) | ||
شناسه دیجیتال (DOI): 10.22059/jvr.2018.124525.2296 | ||
نویسندگان | ||
حمید امانلو؛ غلامرضا نوری* ؛ محمد هرکی نژاد؛ مراد پاشا اسکندری نسب؛ حمیدرضا میرزایی الموتی | ||
گروه علوم دامی، دانشکده کشاورزی دانشگاه زنجان، زنجان، ایران | ||
چکیده | ||
زمینه مطالعه: شناسایی فاکتورهای متابولیکی پیرامون زایش دارای اهمیت بهسزایی است. مهمترین مرحله زندگی میش را میتوان پیش از زایمان و اوایل شیردهی در نظر گرفت که بر سلامت و عملکرد میش و بره تأثیرگذار است. هدف: این مطالعه به منظور بررسی مصرف متیونین محافظتشده بر فاکتورهای متابولیکی میشهای دوقلو آبستن در دوره پیش و پس از زایش و همچنین عملکرد برههای آنها صورت گرفت. روش کار: 16 راس میش افشاری آبستن با وزن بدن kg 3/5±5/91 و روزهای آبستنی 5/1±117 روز در قالب طرح کاملاً تصادفی و به صورت انفرادی به دو جیره غذایی که یکی پایه و دیگری حاوی (3g/kg) مادهخشک از متیونین محافظتشده براساس پژوهشهای پیشین بود، اختصاص یافتند. میشها دو مرتبه در روز و با جیره کاملاً مخلوط تغذیه شدند. مادهخشک مصرفی به صورت روزانه اندازهگیری شد، همچنین خونگیری در روزهای 30 و 15 پیش از زایش و روز 1ام و 30ام پس از زایش از میشها انجام شد، وزن بدن میشها در روزهای40، 20، 10 پیش از زایمان و 1، 10، 20 پس از زایمان اندازهگیری شد. وزن تولد برهها نیز در روزهای 0، 15، 30 و 60 بعد از تولد اندازهگیری شد. نتایج: وزن تولد برههای میشهای دریافت کننده متیونین محافظتشده نسبت به گروه شاهد بالاتر بود (05/0>p)، مصرف متیونین محافظتشده، میزان اوره را کاهش داد (05/0>p) و میزان کلسترول پلاسما پس از زایش را افزایش داد (05/0>p) و میزان پروتئین کل و آلبومین تمایل به معنیداری از خود نشان داد (1/0>p) و سایر فاکتورهای اندازهگیری شده، تفاوت معنیداری نداشتند. نتیجهگیری نهایی: این نتایج نشان میدهد که فراسنجههای خونی با توجه به نزدیک شدن به زایمان تحت تأثیر قرار میگیرد. به علاوه خورانیدن متیونین محافظتشده سبب بهبود افزایش وزن تولد در بره میشها و بهبود برخی فراسنجههای خونی مرتبط با نیتروژن با توجه به اثرات تیمار و متقابل زمان و تیمار میگردد. | ||
کلیدواژهها | ||
میش دوقلو آبستن؛ متیونین محافظتشده؛ پیرامون زایش | ||
عنوان مقاله [English] | ||
Effect of protected methionine supplementation in late lactation on blood metabolites of twin-bearing ewes pre- and post-lambing | ||
نویسندگان [English] | ||
Hamid Amanlou؛ Gholam Reza Noori؛ Mohammad Taher Harakinejad؛ Moradpasha Eskandarinasab؛ Hamid reza Mirzaei Alamouti | ||
Department of Animal Science, Faculty of Agriculture University of Zanjan, Zanjan, Iran | ||
چکیده [English] | ||
BACKGROUND: The rearing of large body size and high ability to twinning by genetic selection and nutritional strategies is expanding. However, lambs’ performance and decreased losses related to the multiple-bearing around lambing can affect the efficiency of multi-bearing. Recognition and control of changes in metabolic factors priparturient have vital importance. Pre-lambing and immediately after lambing could be considered as the most important and critical period of ewe life which affects heath and performance of ewes and lambs. Objectives: This experiment was carried out in order to evaluate the effects of protected methionine supplementation during pre-lambing period on metabolic factors of twin-bearing ewes through priparturient period and their lambs as well. Methods: Sixteen pregnant Afshari ewes weighting 91.5 ± 5.3 kg and 117 ± 1.5 days of pregnancy were randomly assigned to two dietary treatments containing no methionine supplementation and 3gr/kg DM of protected methionine. They were individually fed total mixed ration twice a day. Dry matter intake was recorded daily; the blood samples were drawn on days -30, -15, +1 and +30 related to lambing; ewes’ BWs were measured on days -40, -20, -10, +1, +10 and +20 related to lambing; lambs were weighted on days of birth, +15, +30 and +60. Results: The BW of lambs of ewes supplemented with protected methionine was greater than the control group (p<0.05), protected methionine affected pre-lambing blood urea and albumin concentration (p<0.05), plasma cholesterol was higher in control group (p<0.05) and total protein and albumin tended to be significant (p<0.1) and other blood factors were not influenced by treatments. Conclusions: These results show that blood metabolites are influenced as animals approach the lambing time. In addition, rumen protected methionine resulted in improved birth weight of multi-bearing ewes’ lambs and caused improved blood metabolites related to N, considering the interaction between time and treatment. | ||
کلیدواژهها [English] | ||
Twin-bearing ewes, protected methionine, peripartum | ||
مراجع | ||
Anderson, M. S., He, J., Flowers-Ziegler, J., Devaskar, S. U., Hay Jr, W. W. (2001) Effects of selective hyperglycemia and hyperinsulinemia on glucose transporters in fetal ovine skeletal muscle. Am J Physiol. 281: 1256–1263. ##
Archibeque, S. I., Burns, J. C., Huntington, G. B. (2002) Nitrogen metabolism of beef steers fed endophyte-free tall fescue hay: Effect of ruminally protected methionine supplementation. J Anim Sci. 80: 1344–1351. ##
Baird, G. D. (1981) Lactation, pregnancy and metabolic disorder in the ruminant. Proc Nutr Soc. 40: 115–120. ##
Balıkcı, E., Yıldız, A., Gurdogan, F. (2007) Blood metabolite concentrations during pregnancy and postpartum in Akkaraman ewes. Small Rumin Res. 67: 247–251. ##
Bell, A. W. (1995) Regulation of organic nutrient metabolism during transition from late pregnancy to early lactation. J Anim Sci. 73: 2804-2819. ##
Bell A.W., Ehrhardt R.A. (2000) Regulation of macronutrient partitioning between maternal and conceptus tissues in the pregnant ruminant. In: Ruminant Physiology: Digestion, Metabolism, Growth and Reproduction. Cronje, P.B. (ed.). CABI Publishing, CAB International, Wallingford. p. 275-293. ##
Bickhardt, K., Konig, G. (1985) Blood values of healthy ewes of the Merino and Blackhead breed during parturition. Dtsch Tierarztl Wochenschr. 92: 319–322. ##
Bobe, G., Young, J. W., Beitz, D. C. (2004) Invited review: Pathology, etiology, prevention and treatmentof fatty liver in dairy cows. J Dairy Sci. 87: 3105-3124. ##
Boden, G., Shulman, G. I. (2002) Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction. Eur J Clin Invest. 32: 14–23. ##
Bremersi, R. P. M., Morgan, P. F., McCutcheon, S. N., Purchas, R.W. (1988) Effect of plane of nutrition on energy and nitrogen retention and on plasma urea concentrations in Southdown ram hogget’s from high and low back fat selection lines. New Zealand. J Agri Res. 31: 1-7. ##
Brozostowski, H., Milewski, S., Wasilewska, A., Tanski, Z. (1996) The influence of the reproductive cycle on level of some metabolism indieces in ewe. Arch Vet Polonic. 35: 53-62. ##
Brusemeister, F., Südekum, K. H. (2006) Rumen-protected choline for dairy cows: the in situevaluation of a commercial source and literature evaluation of effects on performance andinteractions between methionine and choline metabolism. Anim Res. 55: 93-104. ##
Butler, W. R. (1998) Review: effect of protein nutrition on ovarian and uterine physiology in dairycattle. J Dairy Sci. 81: 2533–2539. ##
Carroll, D. J., Jerred, M. J., Grummer, R. R., Combs, D. K., Pierson, R. A., Hauser, E. R. (1990) Effects of fat supplementation and inmature alfalfa to concentrate ratio on plasma progesterone, energy balance, and reproductive traits of dairy cattle. J. Dairy Sci. 73: 2855-2863. ##
Chen, Y., Yang, Y., Miller, M. L., Shen, D., Shertzer, H. G., Stringer, K. F., Wang, B., Schneider, S. N., Nebert, D. W., Dalton, T. P. (2007) Hepatocyte-specific Gclc deletion leads to rapid onset of steatosis with mitochondrial injury and liver failure. Hepatology. 45: 1118–1128. ##
Dafoe, J. M., Kott, R. W., Sowell, B. F., Berardinelli, J. G., Davis, K. C., Hatfield, P. G. (2008) Effects of supplemental safflower and vitamin E during late gestation on lamb growth, serum metabolites, and thermogenesis. J Anim Sci. 86: 3194–3202. ##
Dawson, L. E. R., Carson, A. F., Kilpatrick, D. J. (1999) The effect of the digestible undegradable protein concentration of concentrates and protein source offered to ewes in late pregnancy on colostrums production and lamb performance. Anim Feed Sci Technol. 82: 21-36. ##
De Barbieri, I., Montossi, F., Vi˜noles, C., Kenyon, P. R. (2014) Effect of shearing ewes during mid- and late-pregnancy on lamb’s weight at birth and survival to weaning under grazing conditions in Uruguay. Small Rumin Res. 119: 28–32. ##
Dønnem, I., Randby, Å. T., Hektoen, L., Avdem, F., Meling, S., Våge, Å. Ø., Ådnøy, T., Steinheim, G., Waage, S. (2015) Effect of vitamin E supplementation to ewes in late pregnancy on the rate of stillborn lamb. Small Rumin Res. 125: 154–162. ##
Dove, H., Roberds, G. E. (1974) Effect of abomasal infusion ofmethionine, casein and starch plus methionine on the wool. Aust J Agric Res. 25: 945–956. ##
Duehlmeier, R., Fluegge, I., Schwert, B., Parvizi, N., Ganter, M. (2011) Metabolic adaptations to pregnancy and lactation in German Black headed Mutton and Finn sheep ewes with different susceptibilities to pregnancy toxaemia. Small Rumin Res. 96: 178–184. ##
Duehlmeier, R., Noldt, S., Ganter, M. (2013) Pancreatic insulin release and peripheral insulin sensitivity in German black headed mutton and Finish Landrace ewes: evaluation of the role of insulin resistance in the susceptibility to ovine pregnancy toxemia. Domest Anim Endocrinol. 44: 213–221. ##
El-sherif, M.M.A., Assad, F. (2001) Change in some blood constituents of Barki ewes during pregnancy and lactation under semi condition. Small Rumin Res. 40: 269-277. ##
Emmanuel, B., Robblee, A. R. (1984) Cholesterogenesis from propionate: Facts and speculations. Int J Biochem. 16: 907-911. ##
Finkelstein, J. D., Harris, B. J., Martin, J. J., Kyle, W.E. (1982) Regulation of hepatic betaine-homocyteinemethyltransferase by dietary methionine. Biochem Biophys Res Comm. 108: 344-348. ##
Firat, A., Ozpinar, A. (2002) Metabolic profile of pre-pregnancy, pregnancy and early lactation in multiple lambing Sakiz ewes 1. Changes in plasma glucose, 3-hydroxybutyrate and cortisol levels. Ann Nutr Metab. 46: 57–61. ##
Francisco, C. C., Spicer, L. J., Payton, M. E. (2003) Predicting cholesterol, progesterone, and days to ovulation using postpartum metabolic and endocrine measures. J Dairy Sci. 86: 2852-2863. ##
Gently, L. R., Fernandez, J. M., Ward, T. L., White, T. W., Southern, L. L., Bidner, T. D., Thompson, D. L., Horohov, Jr. D .W., Chapa, A. M., Sahlu, T. (1999) Dietary protein and chromium tripicolinate in Suffolk wether lambs: effects on production characteristics, metabolic and hormonal responses, and immune status. J Anim Sci. 77: 1284–1294. ##
Gruffat, D., Durand, D., Chilliard, Y., Williams, P., Bauchart, D. (1997) Hepatic gene expression ofapolipoprotein B100 during early lactation in underfed, high producing dairy cows. J Dairy Sci. 80: 657-666. ##
Goulas, C., Zervas, G., Papadopoulos, G. (2003)Effect of dietary animal fat and methionine on dairy ewes milk yield and milk composition. Anim Feed Sci Technol. 105: 43-35. ##
Hart, I. C. (1983) Endocrine control of nutrient partition in lactating ruminants. Proc Nutr Soc. 42: 181–194. ##
Henze, P., Bickhardt, K., Fuhrmann, H., Sallmann, H. P. (1998) Spontaneous pregnancy toxemia (ketosis) in sheep and the role of insulin. J Vet Med. 45: 255–266. ##
Henze, P., Bickhardt, K., Fuhrmann, H. (1994) The contributions of the hormones insulin, cortisol, somatotropin and total estrogen to the pathogenesis of sheep ketosis. Dtsch Tierarztl Wochenschr. 101: 61–65. ##
Ingvartsen, K. L., Andersen, J. B. (2000) Integration of metabolismand intake regulation: A review focusing on periparturientanimals. J Dairy Sci. 83:1573–1597. ##
Karapehlivan, M., Atakisi, E., Atakisi, O., Yucayurt, R., Pancarci, S. M. (2007) Blood biochemical parameters during the lactation and dry period in Tuj ewes. Small Rumin Res. 73: 267–271. ##
Kleppe, B. B., Aiello, R. J., Grummer, R. R., Armentano, L. E. (1988) Triglyceride accumulation andvery low density lipoprotein secretion by rat and goat hepatocytes in vitro. J Dairy Sci.71: 1813-1822. ##
Liamadis, S., Milis, Ch. (2007) Significance of quality of truly digestible protein on performance of ewes at late pregnancy and early lactation. Small Rumin Res. 71: 67–74. ##
Liker, B., Bačar-Huskić, L., Knežević, M., Rupić1, V., Vranešić, N., Romić, Ž.,Grbeša, D., Mačešić, D., Leto, J., Antunović, Z. Krnić, Ž. (2005) Blood metabolites and haematological indices of pregnant beef cows fed rumen-protected methionine. J Anim Feed Sci. 14: 625–638. ##
Li, Ch., Zhao, G. (2011) Relationships between Methionine Supply, Nitrogen Retention and Plasma Insulin-like Growth Factor-I in Growing Sheep Nourished by Total Intragastric Infusions. Asian-Aust. J Anim Sci. 24: 1393 - 1398 ##
Lynch, G. P., Elsasser, T. H., Jackson, C., Rumsey, T. S., Camp, M. J. (1991) Nitrogen metabolism of lactating ewes fed rumen-protected methionine and lysine. J. Dairy Sci. 74:2268-2276. ##
Marcos, E., Mazur, A., Cardot, P., Rayssinguier, Y. (1990) Theeffects of pregnancyand lactation on serum lipid and Apo lipoprotein B and A-Ilevels in dairy cows. J Anim Physiol Anim Nut. 64: 133-138. ##
Martinov, M. V., Vitvitsky, V. M., Banerjee, R., Ataullakhanov, F. I. (2010) The logic of the hepatic methionine metabolic cycle. Biochim Biophys Acta. 1804: 89–96. ##
Metges, C. C. (2001) Does dietary protein in early life affect the development of adiposity in mammals? J Nutr. 131: 2062–2066. ##
Moallem, U., Rozov, A., Gootwine, E., Honig, H. (2012) Plasma concentrations of key metabolites and insulin in late-pregnant ewes carrying 1 to 5 fetuses. J Anim Sci. 90: 318-324. ##
Ocak, N., Cam, M. A., Kuran, M. (2005) The effect of high dietary protein levels during late gestation on colostrums yield and lamb survival rate in singleton–bearing ewes. Small Rumin Res. 56: 89–96. ##
O’Doherty, J. V., Crosby, T. F. (1998) Blood metabolite concentrations in late pregnant ewes as indicators on nutritional status. J Anim Sci. 66: 675-683. ##
Prior, R. L., Christenson, RK. (1978) Insulin and glucose effects on glucosemetabolism in pregnant and nonpregnant ewes. J Anim Sci. 46: 201–10. ##
Rodriguez, M.N., Tebot, I., Le Bas, A., Niievas, C., Leng, L., Cirio, A. (1996) Renal function and urea handing in pregnant and lactating corriedal ewe. Can J Anim Sci. 76: 469-472. ##
Rook, J.S. (2000). Pregnancy toxemia of ewes, does, and beef cows. Vet. Clin. North Am. Food Anim. Pract. 16: 293–317. ##
Russel, A. J. F. (1984) Means of assessing the adequacy of nutrition of pregnant ewes. Livest Prod Sci. 11, 429-436. ##
Sabbagh, T. A., Swanson, L. V., Thompson, J. M. (1995) The effect of ewe body condition at lambing on colostral immunoglobulin G concentration and lamb performance. J Anim Sci. 73: 2860–2864. ##
Schlumbohm, C., Harmeyer, J. (2004) Hyperketonemia impairs glucose metabolism in pregnant and nonpregnant ewes. J Dairy Sci. 87:350–358. ##
Sevi, A., Taibi, L., Muscio, A., Dell’Aquila, S., Casamassima, D. (1998) Quality of milk as affected by number of lambs and length of suckling. Ital J Food Sci. 10: 229–241. ##
Socha, M. T., Putnam, D. E., Garthwaite, B. D., Whitehouse, N. L.,Kierstead, N. A. (2005) Amino acid supply of Pre- and Postpartum dairycows with Rumen protected Methionine and Lysine. J Dairy Sci. 88: 1113–1126. ##
Strzetelski, J. A., Kowalski, Z. M., Kowalczyk, J., Borowiec, F.,Osięgłowski, S., Ślusarczyk, K. (2009) Protected methionine as a methyl-group donor for dairy cows fed diets with different starch sources in the transition period. J Anim Feed Sci. 18: 28–41. ##
Studer, V. A., Grummer, R. R., Bertics, S., Reynolds, C. K. (1993) Effectof prepartum propylene glycol administration on periparturientfatty liver in dairy cows. J Dairy Sci. 76: 2931–2939. ##
Sun, Z. H., Tan, Z. L., Liu, M. S., Tayo, G. O., Lin, B., Teng, B., Tang, S. X., Wang, J. M., Liao, Y. P., Pan,Y. F., Wang,J. R., Zhao, X. G., Hu, Y. (2007) Effects of dietary methionine and lysine sources on nutrient digestion, nitrogen utilization, and duodenal amino acid flow in growing goats. J Anim Sci. 85: 3340-3347. ##
Tygesen, M. P., Nielsen, M. O., Norgaard, P., Ranvig, H., Harrison, A. P., Tauson, A. H. (2008) Late gestational nutrient restriction: effects on ewes’ metabolic and homeorhetic adaptation, consequences for lamb birth weight and lactation performance. Arch Anim Nutr. 62: 44–59. ##
Vernon, R. G., Clegg, R. A., Flint, D. J. (1981) Metabolism of sheep adipose tissue during pregnancy and lactation. Adaptation and regulation. J Biochem. 200: 307–314. ##
Wang, C., Liu, H. Y., Wang, Y. M., Yang, Z. Q., Liu, J. X.,Wu, Y. M., Yan, T., Ye, H. W. (2010) Effects of dietarysupplementation of methionine and lysine on milkproduction and nitrogen utilization in dairy cows. J Dairy Sci. 93: 3661–3670. ##
Waterman, R. C., Loest, C. A, Bryant, W. D., Peterson, M. K. (2007) Supplemental methionine and urea for gestating beef cows consuming low quality forage diets. J Anim Sci. 85: 731–736. ##
Williams, A. J., Murison, R., Padgett, J. (1988) Metabolism of Sulfur-containing Amino Acids by Pregnant Merino Ewes. Aust J Bioi Sci. 41: 247-59##
Wu, G., Bazer, F. W., Wallace, J. M., Spencer, T. E. (2006) Board-invited review: intrauterine growth retardation: implications for the animal sciences. J Anim Sci. 84: 2316–2337. ##
| ||
آمار تعداد مشاهده مقاله: 416 تعداد دریافت فایل اصل مقاله: 653 |