Silica Boron Sulfonic Acid as Heterogeneous and Highly Efficient Solid Acid Catalyst For the Preparation of Hantzsch 1,4-dihydropyridines Under Solvent-Free | ||
| Journal of Sciences, Islamic Republic of Iran | ||
| مقاله 4، دوره 30، شماره 1، بهار 2019، صفحه 33-40 اصل مقاله (171.84 K) | ||
| نوع مقاله: Short Communications (Notes) | ||
| شناسه دیجیتال (DOI): 10.22059/jsciences.2019.69630 | ||
| نویسندگان | ||
| sami sajjadifar* ؛ Pegah Masoudi | ||
| Department of Chemistry, Payame Noor University, PO BOX 19395-4697 Tehran, Iran | ||
| چکیده | ||
| Silica boron sulfonic acid [SiO2–B(OSO3H)3] as an inexpensive, reusable, and Lewis and Brønsted acid catalyst was successfully synthesized, and used for the one-pot three-components synthesis of biologically active substituted Hantzsch 1,4-dihydropyridine derivatives in the absence of solvent at 90ºC. Silica boron sulfonic acid is attractive and efficient, because it plays in two role as a Lewis acid (by boron atom) and also as a Brønsted acid (by OSO3H group), which can have a better effect in reaction. The reaction was carried out under solvent-free and mild conditions. Silica boron sulfonic acid can be recovered and reused for at least five consecutive runs. | ||
| کلیدواژهها | ||
| Lewis and Brønsted acidic؛ Hantzsch Reaction؛ 1,4-dihydropyridine؛ Solvent-free؛ One-pot condensation | ||
| مراجع | ||
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