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Long-Time Immune Response of Rainbow trout (Oncorhynchus mykiss) to local Yersiniosis Vaccine (Antiyersin) under Farm Condition | ||
Iranian Journal of Veterinary Medicine | ||
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 15 اردیبهشت 1404 | ||
نوع مقاله: Original Articles | ||
شناسه دیجیتال (DOI): 10.22059/ijvm.2025.387191.1005714 | ||
نویسندگان | ||
Fatemeh Yazarloo1؛ Mahdi Soltani* 2؛ Seyed Saeid Mirzargar3؛ Gholamreza Nikbakht4 | ||
1Department of Aquatic Animal Health, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran | ||
2دانشکده دامپزشکی | ||
3دانشکده دامپزشکی- بیماریهای آبزیان | ||
4Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran | ||
چکیده | ||
Background: Yersiniosis, caused by the bacterium Yersinia ruckeri, poses a significant threat to aquaculture, particularly affecting rainbow trout (Oncorhynchus mykiss). This disease leads to substantial economic losses, highlighting the urgent need for effective vaccination strategies to enhance fish health and survival in farming environments. Objectives: This study investigates the long-term immune response of rainbow trout to a locally developed yersiniosis vaccine (Antiyersin) under farm conditions. The research highlights the significant impact of vaccination on fish health and survival, emphasizing the importance of water quality as an environmental factor influencing vaccine efficacy. Methods: The study involved various vaccination methods, including immersion and intraperitoneal injection, with antibody titers measured through ELISA and agglutination methods, as well as leukocyte counts evaluated to assess immune response. Result: Results indicated that the immersion vaccination with a booster dose elicited the highest antibody titers in the ELISA method, while the intraperitoneal vaccination method showed better outcomes in leukocyte counts and agglutination tests. Conclusions: Insights from this research could inform health policies in aquaculture, promoting effective vaccination strategies and enhancing disease management practices. | ||
کلیدواژهها | ||
Agglutination؛ ELISA؛ Leukocyte؛ Vaccine؛ Yersinia ruckeri | ||
آمار تعداد مشاهده مقاله: 45 |