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Hamedi, Mona, Mofidi, Shayan, Fallah, Amirmohammad, Vahedi, Saber. (1404). Molecular and histopathological detection of Bovine Viral Diarrhea Virus in Aborted Fetuses from a Vaccinated Herd around Tehran Province. , (), -. doi: 10.22059/ijvm.2025.387427.1005720
Mona Hamedi; Shayan Mofidi; Amirmohammad Fallah; Saber Vahedi. "Molecular and histopathological detection of Bovine Viral Diarrhea Virus in Aborted Fetuses from a Vaccinated Herd around Tehran Province". , , , 1404, -. doi: 10.22059/ijvm.2025.387427.1005720
Hamedi, Mona, Mofidi, Shayan, Fallah, Amirmohammad, Vahedi, Saber. (1404). 'Molecular and histopathological detection of Bovine Viral Diarrhea Virus in Aborted Fetuses from a Vaccinated Herd around Tehran Province', , (), pp. -. doi: 10.22059/ijvm.2025.387427.1005720
Hamedi, Mona, Mofidi, Shayan, Fallah, Amirmohammad, Vahedi, Saber. Molecular and histopathological detection of Bovine Viral Diarrhea Virus in Aborted Fetuses from a Vaccinated Herd around Tehran Province. , 1404; (): -. doi: 10.22059/ijvm.2025.387427.1005720

Molecular and histopathological detection of Bovine Viral Diarrhea Virus in Aborted Fetuses from a Vaccinated Herd around Tehran Province

Iranian Journal of Veterinary Medicine
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 15 اردیبهشت 1404
نوع مقاله: Original Articles
شناسه دیجیتال (DOI): 10.22059/ijvm.2025.387427.1005720
نویسندگان
Mona Hamedi* 1؛ Shayan Mofidi2؛ Amirmohammad Fallah2؛ Saber Vahedi2
1Department of microbiology and immunology, Faculty of veterinary medicine, University of Tehran, Tehran, Iran
2Student of Veterinary Medicine, Faculty of Veterinary Medicine, Science and Research University, Tehran, Iran.
چکیده
Background: Bovine viral diarrhea virus (BVDV), is known as one of the most important economic diseases affecting many livestock-producing countries. The disease can lead to embryo resorption, abortion, and the birth of weak calves. BVD control strategies include vaccination and implementation of effective biosecurity.
Objectives: The current research with the aim of highlighting the biosecurity principles, investigated the presence of the virus in cases of abortion in a vaccinated dairy herd using molecular and histopathological methods.
Methods: A total of 23 swab samples from abortion secretions, 7 aborted fetuses, and parenchymatous tissues from 2 slaughtered calves with neurological symptoms were sent to the laboratory for the detection of BVDV using Real-time RT-PCR and histopathological examination.
Results: Four aborted fetuses (57.14%) and 15 swab samples (65.22%) were detected positive for BVDV by the molecular test. The two slaughtered calves with neurological symptoms including exophthalmos, ataxia and hydranencephaly were both BVDV positive. The positive samples in the molecular test, showed mild to severe changes related to BVDV infection except of the heart samples. The specific findings included lymphoid tissue depletion in the spleen, multifocal gliosis in the cerebrum, vesicular degeneration in the hepatocytes, multifocal purulent interstitial nephritis, interstitial pneumonia, and multifocal necrotic cryptitis was found in the histopathological examination.
Conclusion: The results of the present research indicate that vaccination alone is not enough to control BVD and strict adherence to biosecurity protocols is as important as vaccination in the prevention and control of the disease.
کلیدواژه‌ها
Abortion؛ Bovine Viral Diarrhea؛ Dairy cattle؛ Histopathology؛ Real time PCR
آمار
تعداد مشاهده مقاله: 77





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