سامانه پشتیبانی خدمات اطلاعات

  اخبار و اعلانات

 آمار

تعداد نشریات161
تعداد شماره‌ها6,573
تعداد مقالات71,037
تعداد مشاهده مقاله125,522,674
تعداد دریافت فایل اصل مقاله98,782,370
Rahaman, S.A.. (1389). Synthesis and in vitro Antibacterial Activity of Some Novel 2-Amino-4, 6-D Derivatives. , 22(1), 27-57.
S.A. Rahaman. "Synthesis and in vitro Antibacterial Activity of Some Novel 2-Amino-4, 6-D Derivatives". , 22, 1, 1389, 27-57.
Rahaman, S.A.. (1389). 'Synthesis and in vitro Antibacterial Activity of Some Novel 2-Amino-4, 6-D Derivatives', , 22(1), pp. 27-57.
Rahaman, S.A.. Synthesis and in vitro Antibacterial Activity of Some Novel 2-Amino-4, 6-D Derivatives. , 1389; 22(1): 27-57.

Synthesis and in vitro Antibacterial Activity of Some Novel 2-Amino-4, 6-D Derivatives

Journal of Sciences, Islamic Republic of Iran
مقاله 4، دوره 22، شماره 1، خرداد 2011، صفحه 27-57    اصل مقاله (210.54 K)
نویسنده
S.A. Rahaman
Nirmala College of Pharmacy
چکیده
Heterocyclic systems are one of the most important classes of organic compounds present in nature or synthesized in laboratory. These compounds posses an array of biological activities and are employed in the treatment of commonly occurring diseases. Keeping this in view, some new 2-amino-4,6-diarylpyrimidine from chalcones were synthesized. Eight novel 2-amino-4,6-diarylpyrimidine derivatives have been prepared by condensation of chalcone derivatives with guanidine hydrochloride. The structures of the synthesized compounds were assigned on the basis of elemental analysis, IR spectra, 1H NMR and Mass spectral data. These compounds were screened for their antibacterial activity. The recorded zone of inhibition showed significant antibacterial activity when compared with reference standard Sparfloxacin.
کلیدواژه‌ها
41-Piperazine acetophenone؛ Pyrimidines؛ Guanidine and Sparfloxacin
عنوان مقاله [English]
Synthesis and in vitro Antibacterial Activity of Some Novel 2-Amino-4, 6-D Derivatives
نویسندگان [English]
S.A. Rahaman
چکیده [English]
Heterocyclic systems are one of the most important classes of organic compounds present in nature or synthesized in laboratory. These compounds posses an array of biological activities and are employed in the treatment of commonly occurring diseases. Keeping this in view, some new 2-amino-4,6-diarylpyrimidine from chalcones were synthesized. Eight novel 2-amino-4,6-diarylpyrimidine derivatives have been prepared by condensation of chalcone derivatives with guanidine hydrochloride. The structures of the synthesized compounds were assigned on the basis of elemental analysis, IR spectra, 1H NMR and Mass spectral data. These compounds were screened for their antibacterial activity. The recorded zone of inhibition showed significant antibacterial activity when compared with reference standard Sparfloxacin.
آمار
تعداد مشاهده مقاله: 1,448
تعداد دریافت فایل اصل مقاله: 2,654





سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب