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SYNTHESIS OF NEW PHASE- 1 METABOLITES OF TWO BARBITURATES | ||
Journal of Sciences, Islamic Republic of Iran | ||
مقاله 12، دوره 1، شماره 5، بهمن 1990 اصل مقاله (290.93 K) | ||
چکیده | ||
The new 4'- hydroxy and 3'- aldehyde phase- 1 metabolites of butobarbitone and pentobarbitone are fully synthesized for the first time. These metabolites were used to idenfity and quantify the natural metabolites in human urine after single and multiple doses of these drugs. The synthesized metobolites have spectral characterizations (IR, NMR, U.V. and mass spectroscopy) consisted with the assigned structures | ||
عنوان مقاله [English] | ||
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چکیده [English] | ||
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آمار تعداد مشاهده مقاله: 984 تعداد دریافت فایل اصل مقاله: 1,207 |