سامانه پشتیبانی خدمات اطلاعات

  اخبار و اعلانات

 آمار

تعداد نشریات158
تعداد شماره‌ها6,225
تعداد مقالات67,685
تعداد مشاهده مقاله114,943,954
تعداد دریافت فایل اصل مقاله89,611,960
. (1380). A NEW STRATEGY FOR THE SYNTHESIS OF TRICYCLIC AND TETRACYCLIC SYSTEMS OF INDOLE ALKALOIDS. , 12(3), -.
. "A NEW STRATEGY FOR THE SYNTHESIS OF TRICYCLIC AND TETRACYCLIC SYSTEMS OF INDOLE ALKALOIDS". , 12, 3, 1380, -.
. (1380). 'A NEW STRATEGY FOR THE SYNTHESIS OF TRICYCLIC AND TETRACYCLIC SYSTEMS OF INDOLE ALKALOIDS', , 12(3), pp. -.
. A NEW STRATEGY FOR THE SYNTHESIS OF TRICYCLIC AND TETRACYCLIC SYSTEMS OF INDOLE ALKALOIDS. , 1380; 12(3): -.

A NEW STRATEGY FOR THE SYNTHESIS OF TRICYCLIC AND TETRACYCLIC SYSTEMS OF INDOLE ALKALOIDS

Journal of Sciences, Islamic Republic of Iran
مقاله 6، دوره 12، شماره 3، آذر 2001    اصل مقاله (137.88 K)
چکیده
Reaction of tryptamine 1 with dimethyl -3-methoxyallylidenemalonate 2 afforded N?-[4,4-bis (methoxycarbonyl)-1,3-butadienyl] tryptamine 3 which in combination with acetylchloride and pyridine in dichloromethane gave N?, N?-[acetyl]-[(4,4-dinethoxycarbonyl) 1,3butadienyl] tryptamine 4. Treatment of 3 with sodium hydroxide afforded 2H[N-(3-indolyl) ethyl] 2-oxo-3-methoxycarbonyl-1-pyridine 5. Cyclization of 2 with trifluoroacetic acid gave methyl-2-(methoxycarbonyl) 4-(2,3,4,9-tetrahydro-1H-pyrido [3,4-b] indole-1-yle) butanoate 6. Heating of the latter in ethylacetate at reflux temperature afforded a new tetracyclic system methyl 4-oxo 1, 4, 6, 7, 12, 12b-hexahydro indolo [2, 3-a] quinolidine 3 carboxylate 7.
عنوان مقاله [English]
-
چکیده [English]
-
آمار
تعداد مشاهده مقاله: 864
تعداد دریافت فایل اصل مقاله: 1,123


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب