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Synthesis and Pharmacological Evaluation of Some Novel Isatin Derivatives for Antimicrobial Activity | ||
| Journal of Sciences, Islamic Republic of Iran | ||
| مقاله 3، دوره 19، شماره 3، آذر 2008 اصل مقاله (169.97 K) | ||
| چکیده | ||
| In the present work, a series of new 5-substituted-3-(4-arylimino)-1-[5-mercapto(1,3,4-oxadiazolyl)]-methyl-indol-2-one (4a-g) have been synthesized by heterocyclization of 5-substituted-3-(4-arylimino)-2-oxo-1-indole acetylhyrazide (3a-g) on treatment with CS2 in ethanolic KOH. The compound 4a was characterized by its elemental analysis, IR, 1HNMR and Mass Spectroscopy. The synthesized compounds (4a-g) were evaluated for in vitro antibacterial activity and antifungal activity against various strains of bacteria and fungi. | ||
| عنوان مقاله [English] | ||
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| چکیده [English] | ||
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آمار تعداد مشاهده مقاله: 934 تعداد دریافت فایل اصل مقاله: 1,730 |
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