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New Homogeneous And Robust Catalyst for Heck and Suzuki Reactions | ||
Journal of Sciences, Islamic Republic of Iran | ||
مقاله 4، دوره 26، شماره 4، اسفند 2015، صفحه 321-325 اصل مقاله (982.94 K) | ||
نوع مقاله: Final File | ||
نویسندگان | ||
B. Mirza* 1؛ M. H. Sayahi2 | ||
12 Department of Applied Chemistry, Faculty of science, Islamic Azad University, Tehran, Islamic Republic of Iran | ||
21 Department of Chemistry, Payame Noor Universtiy (PNU), P.O. Box 19395-3697, Tehran, Islamic Republic of Iran | ||
چکیده | ||
In this work, different ethyl 2,4-dioxo-4-arylbutanoate derivatives were prepared and evaluated for their Src Kinase inhibitory activity. For this purpose, the appropriate substituted acetophenone derivatives reacted with diethyl oxalate in the presence of sodium ethoxide in dried ethanol to give the corresponding products. All compounds showed moderate activities comparing with staurosporine as the reference drug. | ||
کلیدواژهها | ||
Ethyl 2,4-dioxo-4-arylbutanoates؛ Src kinase؛ cancer | ||
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