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حسین پور, صدیقه, بهپور, ناصر, تأدیبی, وحید, رمضان خانی, اعظم. (1396). تأثیر دوازده هفته تمرینات یکپارچۀ حرکتی شناختی بر عامل نوروتروفیک مشتق از مغز (BDNF) سالمندان مبتلا به دمانس. , 9(2), 223-241. doi: 10.22059/jsb.2017.217453.1114
صدیقه حسین پور; ناصر بهپور; وحید تأدیبی; اعظم رمضان خانی. "تأثیر دوازده هفته تمرینات یکپارچۀ حرکتی شناختی بر عامل نوروتروفیک مشتق از مغز (BDNF) سالمندان مبتلا به دمانس". , 9, 2, 1396, 223-241. doi: 10.22059/jsb.2017.217453.1114
حسین پور, صدیقه, بهپور, ناصر, تأدیبی, وحید, رمضان خانی, اعظم. (1396). 'تأثیر دوازده هفته تمرینات یکپارچۀ حرکتی شناختی بر عامل نوروتروفیک مشتق از مغز (BDNF) سالمندان مبتلا به دمانس', , 9(2), pp. 223-241. doi: 10.22059/jsb.2017.217453.1114
حسین پور, صدیقه, بهپور, ناصر, تأدیبی, وحید, رمضان خانی, اعظم. تأثیر دوازده هفته تمرینات یکپارچۀ حرکتی شناختی بر عامل نوروتروفیک مشتق از مغز (BDNF) سالمندان مبتلا به دمانس. , 1396; 9(2): 223-241. doi: 10.22059/jsb.2017.217453.1114

تأثیر دوازده هفته تمرینات یکپارچۀ حرکتی شناختی بر عامل نوروتروفیک مشتق از مغز (BDNF) سالمندان مبتلا به دمانس

نشریه علوم زیستی ورزشی
مقاله 6، دوره 9، شماره 2، شهریور 1396، صفحه 223-241    اصل مقاله (365.88 K)
نوع مقاله: مقاله پژوهشی Released under CC BY-NC 4.0 license I Open Access I
شناسه دیجیتال (DOI): 10.22059/jsb.2017.217453.1114
نویسندگان
صدیقه حسین پور* 1؛ ناصر بهپور2؛ وحید تأدیبی3؛ اعظم رمضان خانی4
1دانشجوی دکتری تخصصی فیزیولوژی ورزش، دانشگاه رازی، کرمانشاه، ایران
2استادیار گروه فیزیولوژی ورزش دانشگاه رازی، کرمانشاه، ایران
3دانشیار گروه فیزیولوژی ورزش دانشگاه رازی، کرمانشاه، ایران
4دکتری تخصصی فیزیولوژی ورزش، دانشکدۀ تربیت بدنی و علوم ورزشی، دانشگاه تهران، ایران
چکیده
 
هدف از تحقیق حاضر بررسی اثر تمرینات یکپارچۀ حرکتی شناختی بر BDNF سالمندان مبتلا به دمانس بود. بدین منظور، 24 مرد سالمند مبتلا به دمانس (12 نفر گروه تجربی و 12 نفر گروه کنترل) به‌عنوان نمونۀ آماری تحقیق انتخاب شدند. برنامۀ تمرینی یک دورۀ دوازده هفته‌ای (هفته‌ای سه جلسه تمرین 45 دقیقه‌ای) تمرینات حرکتی شناختی بود که براساس رهنمودهای کالج آمریکایی طب ورزش (ACSM) اتخاذ شد. پیش و پس از انجام پروتکل تمرینی میزان BDNF و آزمون‌های عملکردی و شناختی ارزیابی شد. به‌منظور تحلیل آماری از آنالیز تحلیل واریانس دوعاملی با اندازه‌های تکراری استفاده شد. یافته­های پژوهش نشان داد که 12 هفته برنامۀ تمرین حرکتی شناختی به افزایش سطوح BDNF (001/0=P)، بهبود نتایج آزمون رسیدن عملکردی (005/0=P)، آزمون بلند شدن و رفتن زمان‌دار (001/0=P)، آزمون تعادلی برگ (001/0=P) و آزمون کوتاه وضعیت ذهنی (015/0P=)، در گروه فعال منجر شد. به‌طور کلی یافته‌های مطالعه نشان داد که تمرین یکپارچۀ حرکتی در آزمودنی‌های مبتلا به دمانس، سبب افزایش سطوح BNDF می‌شود که از نظر بالینی این یافته‌ها اهمیت آمادگی بدنی به‌عنوان یک عامل پیشگیری‌کننده از ابتلا به زوال عقل در آینده را تأیید می‌کند. همچنین این نوع فعالیت، روش تمرینی سودمندی جهت حفظ عملکرد حرکتی و کاهش سرعت کارکردهای ذهنی سالمندان است.
کلیدواژه‌ها
تعادل؛ تمرینات حرکتی شناختی؛ دمانس؛ شناخت؛ سالمند؛ نوروتروفین
عنوان مقاله [English]
The Effect of 12 Weeks of Cognitive Motor Integrated Exercises on Brain-Derived Neurotrophic Factor (BDNF) in the Elderly with Dementia
نویسندگان [English]
Sedigheh Hosseinpour Delavar1؛ Naser Behpour2؛ Vahid Tadibi3؛ Azam Ramezankhani4
1PhD Student in Exercise Physiology, Razi University, Kermanshah, Iran
2Assistant Professor, Department of Exercise Physiology, Razi University, Kermanshah, Iran
3Associate Professor, Department of Exercise Physiology, Razi University, Kermanshah, Iran
4PhD in Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran
چکیده [English]
 
The aim of the present study was to investigate the effect of cognitive motor integrated exercises on BDNF in the elderly with dementia. For this purpose, 24 male elderly with dementia (12 experimental and 12 control (were selected as the statistical sample. The program consisted of 12 weeks of (3 sessions per week, 45 minutes per session (cognitive motor exercises according to the guidelines of American College of Sport Medicine (ACSM). Before and after the exercise protocol, BDNF and cognitive and functional tests were evaluated. ANOVA with repeated measures was used for data analysis. The results showed that 12 weeks of cognitive motor protocol increased BDNF (P=0.001) and improved the results of functional reach test (P=0.005), timed up and go test (P=0.001), Berg balance scale (P=0.001) and mini–mental state examination (P=0.015) in the active group. In general, these findings showed that motor integrated exercise in the elderly with dementia increased BNDF levels. These findings clinically confirm the importance of physical fitness as a factor which prevents dementia in the future. Also, this type of activity is a beneficial training method to maintain motor function and to reduce the rate of mental functioning in the elderly.
کلیدواژه‌ها [English]
balance, Cognition, cognitive motor exercises, dementia, Elderly, neurotrophin
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