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An Approach for Treatment Programming in Intensity Modulated Radiation Therapy (IMRT) | ||
| Advances in Industrial Engineering | ||
| مقاله 12، دوره 52، شماره 1، تیر 2018، صفحه 113-124 اصل مقاله (870.53 K) | ||
| نوع مقاله: Research Paper | ||
| شناسه دیجیتال (DOI): 10.22059/jieng.2018.225242.1302 | ||
| نویسندگان | ||
| Mehdi Najafi* ؛ Mahsa Faridmehr | ||
| Department of Industrial Engineering, Sharif University of Technology, Tehran, Iran | ||
| چکیده | ||
| Intensity modulated radiation therapy is one of the most commonly procedures used for delivering radiation to cancerous tissues. It aims to deliver the prescribed dose in the target volume while minimizing damage to the nearby healthy organs. In this procedure, two decisions being very important are selecting the beam angles and calculating the beam intensities. Although beam angle selection (beam angle optimization) is one of the most important decisions in this procedure, it is often be made manually and based on radio therapist experience and intuition. In order to overcome this drawback, this paper proposes a hybrid approach for automated beam angle selection and intensity computation. The proposed approach first finds a good feasible solution, and then use this solution as a starting point in local neighborhood search to find the local optimal solution. As the results of numerical experiments demonstrate, the proposed hybrid-approach, compared to its corresponding stand-alone methods, finds a better solution quickly and consistently. | ||
| کلیدواژه‌ها | ||
| Beam Angle Optimization؛ Fluence Map Optimization؛ Intensity Modulated Radiation Therapy؛ Treatment Programming | ||
| عنوان مقاله [English] | ||
| رویکردی برای برنامه‌ریزی طرح درمان در پرتودرمانی با شدت تنظیم‌شده (IMRT) | ||
| نویسندگان [English] | ||
| مهدی نجفی؛ مهسا فریدمهر | ||
| استادیار دانشکدة مهندسی صنایع، دانشگاه صنعتی شریف | ||
| چکیده [English] | ||
| پرتودرمانی با شدت تنظیم‌شده روشی رایج برای انتقال اشعه به بافت سرطانی، با هدف انتقال دوز تجویزشده به حجم هدف و کاهش آسیب به اندام‌های سالم اطراف تومور است. به‌طورمعمول، در این فرایند دو تصمیم اهمیت زیادی دارد: انتخاب زوایای پرتو و محاسبة شدت پرتوها. علی‌رغم اینکه انتخاب زوایای پرتو (بهینه‌سازی زوایای پرتو) در این مسائل بسیار اهمیت دارد، اغلب براساس تجربه انجام شده است و دقت کافی ندارد. برای حل این مشکل، پژوهش حاضر بر آن است تا چارچوبی ترکیبی برای انتخاب خودکار زوایای پرتو و محاسبة شدت پرتوها در این روش رادیوتراپی ارائه کند. رویکرد ارائه‌شده ابتدا با استفاده از روش‌های ابتکاری، نقطه‌ای شدنی با کیفیت خوب برای مسئله پیدا کرده سپس آن را به‌عنوان نقطة شروع در الگوریتم جست‌وجوی همسایگی برای یافتن بهینة محلی به‌کار گرفته است. با توجه به نتایج محاسباتی درمی‌یابیم که استفاده از این رویکرد ترکیبی به‌جای رویکردهای انفرادی در زمان کوتاه‌تر به جواب بهینة محلی با کیفیت خوب دست پیدا می‌کند. | ||
| کلیدواژه‌ها [English] | ||
| برنامه‌ریزی درمان, بهینه‌سازی جهت پرتو, بهینه‌سازی نقشة شار, پرتودرمانی با شدت تنظیم‌شده | ||
| مراجع | ||
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