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sajjadifar, sami, Amini, Issa, Navabi, Z., Jabbari, Hadi, Pouralimardan, Omidali. (1398). The Chemoselective Fischer’s Synthesis of Indolenine Derivatives By iso-Butyric Acid As A Weak Organic Acid Catalyst. , 30(2), 129-134. doi: 10.22059/jsciences.2019.284702.1007424
sami sajjadifar; Issa Amini; Z. Navabi; Hadi Jabbari; Omidali Pouralimardan. "The Chemoselective Fischer’s Synthesis of Indolenine Derivatives By iso-Butyric Acid As A Weak Organic Acid Catalyst". , 30, 2, 1398, 129-134. doi: 10.22059/jsciences.2019.284702.1007424
sajjadifar, sami, Amini, Issa, Navabi, Z., Jabbari, Hadi, Pouralimardan, Omidali. (1398). 'The Chemoselective Fischer’s Synthesis of Indolenine Derivatives By iso-Butyric Acid As A Weak Organic Acid Catalyst', , 30(2), pp. 129-134. doi: 10.22059/jsciences.2019.284702.1007424
sajjadifar, sami, Amini, Issa, Navabi, Z., Jabbari, Hadi, Pouralimardan, Omidali. The Chemoselective Fischer’s Synthesis of Indolenine Derivatives By iso-Butyric Acid As A Weak Organic Acid Catalyst. , 1398; 30(2): 129-134. doi: 10.22059/jsciences.2019.284702.1007424

The Chemoselective Fischer’s Synthesis of Indolenine Derivatives By iso-Butyric Acid As A Weak Organic Acid Catalyst

Journal of Sciences, Islamic Republic of Iran
مقاله 4، دوره 30، شماره 2، تیر 2019، صفحه 129-134    اصل مقاله (138.77 K)
نوع مقاله: Note
شناسه دیجیتال (DOI): 10.22059/jsciences.2019.284702.1007424
نویسندگان
sami sajjadifar* ؛ Issa Amini؛ Z. Navabi؛ Hadi Jabbari؛ Omidali Pouralimardan
Department of Chemistry, Payame Noor University, PO BOX19395-469 Tehran, Islamic Republic of Iran
چکیده
Iso-butyric acid as a new, simple, and expensive solvent/catalyst was successfully used for the chemoselective Fischer’s synthesis of indolenines derivatives 3a-r by one-pot condensation reaction of various phenylhydrazines 1a-e with the substituted acetophenones 2a-c at reflux conditions. In this protocol, all products 3a-r were obtained in high yields and short reaction time. The structures of the product were established with spectroscopic data of 1H NMR, 13C-NMR, and FT-IR.
کلیدواژه‌ها
Fischer’s synthesis؛ Indolenines؛ 3H-Indole؛ Phenylhydrazine؛ Iso-butyric acid
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