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بررسی اثر تجویز خوراکی آیور مکتین بر برخی پارامترهای هماتولوژی و بیوشیمیایی خون الاغ (اکووس آسینوس) | ||
| مجله تحقیقات دامپزشکی (Journal of Veterinary Research) | ||
| مقاله 8، دوره 63، شماره 3، مهر 1387، صفحه 215-220 اصل مقاله (148.53 K) | ||
| نویسندگان | ||
| خلیل بدیعی1؛ فرانک ابنا رودحله1؛ اردوان نوروزی اصل2؛ مهرداد پورجعفر1؛ بهروز نیک احوال3 | ||
| 1گروه علوم درمانگاهی دانشکده دامپزشکی شیراز | ||
| 2دانشکده دامپزشکی دانشگاه آزاد اسلامی کازرون | ||
| 3گروه دامپزشکی دانشگاه آزاد اسلامی واحد بجنورد | ||
| چکیده | ||
| Five healthy adult male Iranian donkeys (Equus asinus) were selected and Ivermectin (0.2, 0.6 and 0.9 mglkg, orally at different times) for 14 days was administered. Before dosing, control blood samples were taken on day O. Blood samples were taken on days 1,2,3,7 and 14 following ivermectin administration at different doses. The results showed that the activity of serumAST and LDH increased on days 7 and 14 following ivermectin (0.2, 0.6 and 0.9 mglkg, orally) administration (p<0.05). ALP activity and BUN concentration increased significantly on day 14 following ivermectin (0.2, 0.6 and 0.9 mglkg, orally) administration (p<0.05). Changes of ablumin, creatinin,glucose, total protein, Phosphorous and calcium concentrations and hemoglobin, PCV, MCH, MCHC, MCV and percentages of neutrophils, eosinophils, monocytes, lymphocytes and platelet numbers were not significant (p>0.05). As it was shown in short term, no abnormal clinical and laboratory findings were detected following different oral doses of ivermectin and it seems that the drug can be safely administered to this species | ||
| عنوان مقاله [English] | ||
| EFFECT OF ORALLY ADMINISTERED IVERMECTIN ON SOME BLOOD HAEMATOLOGICALAND BIOCHEMICAL FACTORS IN DONKEYS (EQQU SASINUS) | ||
| نویسندگان [English] | ||
| Kalil Badiei1؛ Faranak Abnaroodhele1؛ Ardavan Nowrooziasl2؛ Mehrdad Pourjafar1؛ Behrouz Nikahval3 | ||
| چکیده [English] | ||
| Five healthy adult male Iranian donkeys (Equus asinus) were selected and Ivermectin (0.2, 0.6 and 0.9 mglkg, orally at different times) for 14 days was administered. Before dosing, control blood samples were taken on day O. Blood samples were taken on days 1,2,3,7 and 14 following ivermectin administration at different doses. The results showed that the activity of serumAST and LDH increased on days 7 and 14 following ivermectin (0.2, 0.6 and 0.9 mglkg, orally) administration (p<0.05). ALP activity and BUN concentration increased significantly on day 14 following ivermectin (0.2, 0.6 and 0.9 mglkg, orally) administration (p<0.05). Changes of ablumin, creatinin,glucose, total protein, Phosphorous and calcium concentrations and hemoglobin, PCV, MCH, MCHC, MCV and percentages of neutrophils, eosinophils, monocytes, lymphocytes and platelet numbers were not significant (p>0.05). As it was shown in short term, no abnormal clinical and laboratory findings were detected following different oral doses of ivermectin and it seems that the drug can be safely administered to this species | ||
| کلیدواژه‌ها [English] | ||
| biochemistrya, Blood, donkey., haematology, Ivermectin | ||
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